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The Regulatory Roles of Mitogen-Activated Protein Kinase (MAPK) Pathways in Health and Diabetes: Lessons Learned from the Pancreatic β-Cell

BACKGROUND: Glucose-stimulated insulin secretion (GSIS) from the pancreatic β-cell involves several intracellular metabolic events which lead to the translocation of insulin granules towards the membrane for fusion and release. It is well established that loss of β-cell function and decreased GSIS u...

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Publicat a:Recent Pat Endocr Metab Immune Drug Discov
Autors principals: Sidarala, Vaibhav, Kowluru, Anjaneyulu
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685434/
https://ncbi.nlm.nih.gov/pubmed/27779078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872214810666161020154905
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