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Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

Dysfunction of the blood-brain barrier (BBB) contributes significantly to the pathogenesis of several neuroinflammatory diseases, including multiple sclerosis (MS). Potential players that regulate BBB function are the liver X receptors (LXRs), which are ligand activated transcription factors compris...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wouters, Elien, de Wit, Nienke M., Vanmol, Jasmine, van der Pol, Susanne M. A., van het Hof, Bert, Sommer, Daniela, Loix, Melanie, Geerts, Dirk, Gustafsson, Jan Ake, Steffensen, Knut R., Vanmierlo, Tim, Bogie, Jeroen F. J., Hendriks, Jerome J. A., de Vries, Helga E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685401/
https://ncbi.nlm.nih.gov/pubmed/31417573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01811
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