Altered PPARγ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple Sclerosis

Macrophages play a crucial role during the pathogenesis of multiple sclerosis (MS), a neuroinflammatory autoimmune disorder of the central nervous system. Important regulators of the metabolic and inflammatory phenotype of macrophages are liver X receptors (LXRs) and peroxisome proliferator-activate...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wouters, Elien, Grajchen, Elien, Jorissen, Winde, Dierckx, Tess, Wetzels, Suzan, Loix, Melanie, Tulleners, Marie Paule, Staels, Bart, Stinissen, Piet, Haidar, Mansour, Bogie, Jeroen F.J., Hendriks, Jerome J.A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731422/
https://ncbi.nlm.nih.gov/pubmed/33297574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239329
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