Myelin alters the inflammatory phenotype of macrophages by activating PPARs

BACKGROUND: Foamy macrophages, containing myelin degradation products, are abundantly found in active multiple sclerosis (MS) lesions. Recent studies have described an altered phenotype of macrophages after myelin internalization. However, mechanisms by which myelin affects the phenotype of macropha...

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Detalhes bibliográficos
Main Authors: Bogie, Jeroen FJ, Jorissen, Winde, Mailleux, Jo, Nijland, Philip G, Zelcer, Noam, Vanmierlo, Tim, Van Horssen, Jack, Stinissen, Piet, Hellings, Niels, Hendriks, Jerome JA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893408/
https://ncbi.nlm.nih.gov/pubmed/24252308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-43
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