Myelin alters the inflammatory phenotype of macrophages by activating PPARs

BACKGROUND: Foamy macrophages, containing myelin degradation products, are abundantly found in active multiple sclerosis (MS) lesions. Recent studies have described an altered phenotype of macrophages after myelin internalization. However, mechanisms by which myelin affects the phenotype of macropha...

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Autors principals: Bogie, Jeroen FJ, Jorissen, Winde, Mailleux, Jo, Nijland, Philip G, Zelcer, Noam, Vanmierlo, Tim, Van Horssen, Jack, Stinissen, Piet, Hellings, Niels, Hendriks, Jerome JA
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893408/
https://ncbi.nlm.nih.gov/pubmed/24252308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-43
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