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Myelin alters the inflammatory phenotype of macrophages by activating PPARs
BACKGROUND: Foamy macrophages, containing myelin degradation products, are abundantly found in active multiple sclerosis (MS) lesions. Recent studies have described an altered phenotype of macrophages after myelin internalization. However, mechanisms by which myelin affects the phenotype of macropha...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893408/ https://ncbi.nlm.nih.gov/pubmed/24252308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-43 |
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