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Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke

By releasing glutamate, astrocytes actively regulate synaptic transmission and also contribute to excitotoxicity in neurological diseases. However, the mechanisms of astrocytic glutamate release have been debated. Here, we report non-vesicular release of glutamate through the glutamate-permeable vol...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Yang, Junhua, Vitery, Maria del Carmen, Chen, Jianan, Osei-Owusu, James, Chu, Jiachen, Qiu, Zhaozhu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685291/
https://ncbi.nlm.nih.gov/pubmed/30982627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.03.029
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