Synthesis, anti-leishmanial and molecular docking study of bis-indole derivatives

We have synthesized new series of bisindole analogs (1–27), characterized by (1)HNMR and HR-EI-MS and evaluated for their anti-leishmanial potential. All compounds showed outstanding inhibitory potential with IC(50) values ranging from 0.7 ± 0.01 to 13.30 ± 0.50 µM respectively when compared with st...

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Detalhes bibliográficos
Publicado no:BMC Chem
Main Authors: Taha, Muhammad, Uddin, Imad, Gollapalli, Mohammed, Almandil, Noor Barak, Rahim, Fazal, Farooq, Rai Khalid, Nawaz, Muhammad, Ibrahim, Mohamed, Alqahtani, Mohammed A., Bamarouf, Yasser A., Selvaraj, Manikandan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685257/
https://ncbi.nlm.nih.gov/pubmed/31410413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0617-4
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