An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons

BACKGROUND: Brain microvascular endothelial cells (BMECs) astrocytes, neurons, and pericytes form the neurovascular unit (NVU). Interactions with NVU cells endow BMECs with extremely tight barriers via the expression of tight junction proteins, a host of active efflux and nutrient transporters, and...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Canfield, Scott G., Stebbins, Matthew J., Faubion, Madeline G., Gastfriend, Benjamin D., Palecek, Sean P., Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685239/
https://ncbi.nlm.nih.gov/pubmed/31387594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0145-6
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