An Isogenic Blood-Brain Barrier Model Comprising Brain Endothelial Cells, Astrocytes and Neurons Derived from Human Induced Pluripotent Stem Cells

The blood-brain barrier (BBB) is critical in maintaining a physical and metabolic barrier between the blood and the brain. The BBB consists of brain microvascular endothelial cells (BMECs) that line the brain vasculature and combine with astrocytes, neurons and pericytes to form the neurovascular un...

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Vydáno v:J Neurochem
Hlavní autoři: Canfield, Scott G., Stebbins, Matthew J., Morales, Bethsymarie Soto, Asai, Shusaku W., Vatine, Gad D., Svendsen, Clive N., Palecek, Sean P., Shusta, Eric V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339046/
https://ncbi.nlm.nih.gov/pubmed/27935037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13923
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