Differentiation and Characterization of Human Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

The blood-brain barrier (BBB) is a critical component of the central nervous system (CNS) that regulates the flux of material between the blood and the brain. Because of its barrier properties, the BBB creates a bottleneck to CNS drug delivery. Human in vitro BBB models offer a potential tool to scr...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Stebbins, Matthew J., Wilson, Hannah K., Canfield, Scott G., Qian, Tongcheng, Palecek, Sean P., Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848177/
https://ncbi.nlm.nih.gov/pubmed/26518252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.10.016
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