Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties

Brain pericytes play important roles in the formation and maintenance of the neurovascular unit (NVU), and their dysfunction has been implicated in central nervous system disorders. While human pluripotent stem cells (hPSCs) have been used to model other NVU cell types, including brain microvascular...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Stebbins, Matthew J., Gastfriend, Benjamin D., Canfield, Scott G., Lee, Ming-Song, Richards, Drew, Faubion, Madeline G., Li, Wan-Ju, Daneman, Richard, Palecek, Sean P., Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415958/
https://ncbi.nlm.nih.gov/pubmed/30891496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau7375
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