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Relating evolutionary selection and mutant clonal dynamics in normal epithelia

Cancer develops from mutated cells in normal tissues. Whether somatic mutations alter normal cell dynamics is key to understanding cancer risk and guiding interventions to reduce it. An analysis of the first incomplete moment of size distributions of clones carrying cancer-associated mutations in no...

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Bibliografische gegevens
Gepubliceerd in:J R Soc Interface
Hoofdauteurs: Hall, Michael W. J., Jones, Philip H., Hall, Benjamin A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685019/
https://ncbi.nlm.nih.gov/pubmed/31362624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0230
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