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Relating evolutionary selection and mutant clonal dynamics in normal epithelia

Cancer develops from mutated cells in normal tissues. Whether somatic mutations alter normal cell dynamics is key to understanding cancer risk and guiding interventions to reduce it. An analysis of the first incomplete moment of size distributions of clones carrying cancer-associated mutations in no...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Hall, Michael W. J., Jones, Philip H., Hall, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685019/
https://ncbi.nlm.nih.gov/pubmed/31362624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0230
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