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Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Iron is vital for nearly all living organisms, but during infection, not readily available to pathogens. Infectious bacteria therefore depend on specialized mechanisms to survive when iron is limited. These mechanisms make attractive targets for new drugs. Here, by genome-wide phenotypic profiling,...

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書目詳細資料
發表在:Sci Rep
Main Authors: Dragset, Marte S., Ioerger, Thomas R., Zhang, Yanjia J., Mærk, Mali, Ginbot, Zekarias, Sacchettini, James C., Flo, Trude H., Rubin, Eric J., Steigedal, Magnus
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684656/
https://ncbi.nlm.nih.gov/pubmed/31388080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47905-y
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