Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Iron is vital for nearly all living organisms, but during infection, not readily available to pathogens. Infectious bacteria therefore depend on specialized mechanisms to survive when iron is limited. These mechanisms make attractive targets for new drugs. Here, by genome-wide phenotypic profiling,...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Dragset, Marte S., Ioerger, Thomas R., Zhang, Yanjia J., Mærk, Mali, Ginbot, Zekarias, Sacchettini, James C., Flo, Trude H., Rubin, Eric J., Steigedal, Magnus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684656/
https://ncbi.nlm.nih.gov/pubmed/31388080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47905-y
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