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Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Iron is vital for nearly all living organisms, but during infection, not readily available to pathogens. Infectious bacteria therefore depend on specialized mechanisms to survive when iron is limited. These mechanisms make attractive targets for new drugs. Here, by genome-wide phenotypic profiling,...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Dragset, Marte S., Ioerger, Thomas R., Zhang, Yanjia J., Mærk, Mali, Ginbot, Zekarias, Sacchettini, James C., Flo, Trude H., Rubin, Eric J., Steigedal, Magnus
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684656/
https://ncbi.nlm.nih.gov/pubmed/31388080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47905-y
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