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The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis

Thalidomide is widely used for several diseases; however, it causes malformations in embryos exposed during pregnancy. The complete understanding of the mechanisms by which thalidomide affects the embryo development has not yet been obtained. The phenotypic similarity makes TE a phenocopy of syndrom...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Gomes, Julia do Amaral, Kowalski, Thayne Woycinck, Fraga, Lucas Rosa, Macedo, Gabriel S., Sanseverino, Maria Teresa Vieira, Schuler-Faccini, Lavínia, Vianna, Fernanda Sales Luiz
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684595/
https://ncbi.nlm.nih.gov/pubmed/31388035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47739-8
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