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Thermostability as a highly dependent prion strain feature

Prion diseases are caused by the conversion of physiological PrP(C) into the pathogenic misfolded protein PrP(Sc), conferring new properties to PrP(Sc) that vary upon prion strains. In this work, we analyze the thermostability of three prion strains (BSE, RML and 22L) that were heated at 98 °C for 2...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Moudjou, Mohammed, Espinosa, Juan Carlos, Béringue, Vincent, Torres, Juan María
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684573/
https://ncbi.nlm.nih.gov/pubmed/31388046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47781-6
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