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Thermostability as a highly dependent prion strain feature

Prion diseases are caused by the conversion of physiological PrP(C) into the pathogenic misfolded protein PrP(Sc), conferring new properties to PrP(Sc) that vary upon prion strains. In this work, we analyze the thermostability of three prion strains (BSE, RML and 22L) that were heated at 98 °C for 2...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Moudjou, Mohammed, Espinosa, Juan Carlos, Béringue, Vincent, Torres, Juan María
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684573/
https://ncbi.nlm.nih.gov/pubmed/31388046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47781-6
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