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Silencing of aberrant secretory protein expression by disease-associated mutations
Signal Recognition Particle (SRP) recognizes signal sequences of secretory proteins and targets them to the endoplasmic reticulum membrane for translocation. Many human diseases are connected with defects in signal sequences. The current dogma states that the molecular basis of the disease-associate...
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| Опубликовано в: : | J Mol Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684239/ https://ncbi.nlm.nih.gov/pubmed/31100385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.05.011 |
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