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Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls

Aberrant, misfolded, and mislocalized proteins are often toxic to cells and result in many human diseases. All proteins and their mRNA templates are subject to quality control. There are several distinct mechanisms that control the quality of mRNAs and proteins during translation at the ribosome. mR...

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Udgivet i:Front Genet
Main Authors: Karamyshev, Andrey L., Karamysheva, Zemfira N.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180196/
https://ncbi.nlm.nih.gov/pubmed/30337940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00431
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