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Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls

Aberrant, misfolded, and mislocalized proteins are often toxic to cells and result in many human diseases. All proteins and their mRNA templates are subject to quality control. There are several distinct mechanisms that control the quality of mRNAs and proteins during translation at the ribosome. mR...

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Veröffentlicht in:Front Genet
Hauptverfasser: Karamyshev, Andrey L., Karamysheva, Zemfira N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180196/
https://ncbi.nlm.nih.gov/pubmed/30337940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00431
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