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Trametinib in the treatment of melanoma
INTRODUCTION: Aberrant Mitogen Activated Protein Kinase (MAPK) pathway signaling is a hallmark of melanoma. Mitogen/Extracellular signal-regulated Kinase (MEK) 1/2 are integral components of MAPK signaling. Several MEK inhibitors have demonstrated activity as single agents and in combination with ot...
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| Gepubliceerd in: | Expert Opin Biol Ther |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684215/ https://ncbi.nlm.nih.gov/pubmed/25812921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1026323 |
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