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Trametinib in the treatment of melanoma
INTRODUCTION: Aberrant Mitogen Activated Protein Kinase (MAPK) pathway signaling is a hallmark of melanoma. Mitogen/Extracellular signal-regulated Kinase (MEK) 1/2 are integral components of MAPK signaling. Several MEK inhibitors have demonstrated activity as single agents and in combination with ot...
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| Publicado no: | Expert Opin Biol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684215/ https://ncbi.nlm.nih.gov/pubmed/25812921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1026323 |
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