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Molecular Pathways: Targeting NRAS in Melanoma and Acute Myelogenous Leukemia
Successful targeting of specific oncogenic “driver” mutations with small-molecule inhibitors has represented a major advance in cancer therapeutics over the last 10–15 years. The most common activating oncogene in human malignancy, RAS (rat sarcoma), has proved to be an elusive target. Activating mu...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134689/ https://ncbi.nlm.nih.gov/pubmed/24895460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3270 |
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