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Clinically relevant genes and regulatory pathways associated with NRAS(Q61) mutations in melanoma through an integrative genomics approach
Therapies such as BRAF inhibitors have become standard treatment for melanoma patients whose tumors harbor activating BRAF(V600) mutations. However, analogous therapies for inhibiting NRAS mutant signaling have not yet been well established. In this study, we performed an integrative analysis of DNA...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385866/ https://ncbi.nlm.nih.gov/pubmed/25537510 |
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