Connecting signaling and metabolic pathways in EGF receptor-mediated oncogenesis of glioblastoma

As malignant transformation requires synchronization of growth-driving signaling (S) and metabolic (M) pathways, defining cancer-specific S-M interconnected networks (SMINs) could lead to better understanding of oncogenic processes. In a systems-biology approach, we developed a mathematical model fo...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Bag, Arup K., Mandloi, Sapan, Jarmalavicius, Saulius, Mondal, Susmita, Kumar, Krishna, Mandal, Chhabinath, Walden, Peter, Chakrabarti, Saikat, Mandal, Chitra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684045/
https://ncbi.nlm.nih.gov/pubmed/31386654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007090
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