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Cholesterol Corrects Altered Conformation of MHC-II Protein in Leishmania donovani Infected Macrophages: Implication in Therapy

BACKGROUND: Previously we reported that Kala-azar patients show progressive decrease in serum cholesterol as a function of splenic parasite burden. Splenic macrophages (MΦ) of Leishmania donovani (LD) infected mice show decrease in membrane cholesterol, while LD infected macrophages (I-MΦ) show defe...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Roy, Koushik, Mandloi, Sapan, Chakrabarti, Saikat, Roy, Syamal
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877013/
https://ncbi.nlm.nih.gov/pubmed/27214205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004710
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