Needle Puncture Injury Causes Acute and Long-Term Mechanical Deficiency in a Mouse Model of Intervertebral Disc Degeneration

Low back pain is a significant socioeconomic burden and intervertebral disc degeneration has been implicated as a cause. A reliable animal model of disc degeneration is necessary to evaluate therapeutics, and functional metrics are essential to quantify their benefit. To this end, needle puncture in...

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Bibliographic Details
Published in:J Orthop Res
Main Authors: Martin, John T., Gorth, Deborah J., Beattie, Elizabeth E., Harfe, Brian D., Smith, Lachlan J., Elliott, Dawn M.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684036/
https://ncbi.nlm.nih.gov/pubmed/23553925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22355
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