Intervertebral Disc Degeneration Induced by Needle Puncture and Ovariectomy: A Rat Coccygeal Model

OBJECTIVES: To establish a novel animal model of intervertebral disc degeneration (IVDD) in rats and to investigate the effect of 17β-estradiol (E2) intervention in this model. METHODS: This study was divided into two parts: animal model (four groups: Sham, ovariectomy (OVX), Puncture, and OVX+Punct...

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發表在:Biomed Res Int
Main Authors: Tian, Tao, Wang, Haidong, Li, Zhaohui, Yang, Sidong, Ding, Wenyuan
格式: Artigo
語言:Inglês
出版: Hindawi 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147532/
https://ncbi.nlm.nih.gov/pubmed/34055972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5510124
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