The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes

The generation of protective humoral immunity after vaccination relies on the productive interaction between antigen-specific B cells and T follicular helper (Tfh) cells. Despite the central role of Tfh cells in vaccine responses, there is currently no validated way to enhance their differentiation...

詳細記述

保存先:
書誌詳細
出版年:J Exp Med
主要な著者: Hill, Danika L., Pierson, Wim, Bolland, Daniel J., Mkindi, Catherine, Carr, Edward J., Wang, Jiong, Houard, Sophie, Wingett, Steven W., Audran, Regine, Wallin, Elizabeth F., Jongo, Said A., Kamaka, Kassim, Zand, Martin, Spertini, Francois, Daubenberger, Claudia, Corcoran, Anne E., Linterman, Michelle A.
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2019
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683991/
https://ncbi.nlm.nih.gov/pubmed/31175140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190301
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