The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes

The generation of protective humoral immunity after vaccination relies on the productive interaction between antigen-specific B cells and T follicular helper (Tfh) cells. Despite the central role of Tfh cells in vaccine responses, there is currently no validated way to enhance their differentiation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Hill, Danika L., Pierson, Wim, Bolland, Daniel J., Mkindi, Catherine, Carr, Edward J., Wang, Jiong, Houard, Sophie, Wingett, Steven W., Audran, Regine, Wallin, Elizabeth F., Jongo, Said A., Kamaka, Kassim, Zand, Martin, Spertini, Francois, Daubenberger, Claudia, Corcoran, Anne E., Linterman, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683991/
https://ncbi.nlm.nih.gov/pubmed/31175140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190301
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados