Combined Exposure of Activated Intestinal Epithelial Cells to Nondigestible Oligosaccharides and CpG-ODN Suppresses Th2-Associated CCL22 Release While Enhancing Galectin-9, TGFβ, and Th1 Polarization

BACKGROUND: Short-chain galacto- and long-chain fructo-oligosaccharides (scGOS/lcFOS) and CpG-ODN affect intestinal epithelial cells (IEC). Epithelial IL1α may contribute to allergic sensitization via autocrine mediator release affecting dendritic cells (DC). We studied whether IL1α contributes to T...

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Detalles Bibliográficos
Publicado en:Mediators Inflamm
Main Authors: Overbeek, Saskia A., Kostadinova, Atanaska I., Boks, Martine A., Hayen, Simone M., de Jager, Wilco, van't land, Belinda, Knippels, Leon M., Garssen, Johan, Willemsen, Linette E. M.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683774/
https://ncbi.nlm.nih.gov/pubmed/31427886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8456829
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