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Exposure of Intestinal Epithelial Cells to 2′-Fucosyllactose and CpG Enhances Galectin Release and Instructs Dendritic Cells to Drive Th1 and Regulatory-Type Immune Development

Intestinal epithelial cells (IEC) release immunomodulatory galectins upon exposure to CpG DNA (mimicking bacterial triggers) and short-chain galacto- and long-chain fructo-oligosaccharides (GF). This study aims to investigate the immunomodulatory properties of 2′-fucosyllactose (2′-FL), a non-digest...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Ayechu-Muruzabal, Veronica, Overbeek, Saskia A., Kostadinova, Atanaska I., Stahl, Bernd, Garssen, Johan, van’t Land, Belinda, Willemsen, Linette E.M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278199/
https://ncbi.nlm.nih.gov/pubmed/32438601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10050784
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