Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine

BACKGROUND: Studies in mice suggest that perturbations of the GDNF-Ret signaling pathway are a major genetic cause of congenital anomalies of the kidney and urinary tract (CAKUT). Mutations in Sprouty1, an intracellular Ret inhibitor, results in supernumerary kidneys, megaureters, and hydronephrosis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Soc Nephrol
Prif Awduron: Vaquero, Marta, Cuesta, Sara, Anerillas, Carlos, Altés, Gisela, Ribera, Joan, Basson, M. Albert, Licht, Jonathan D., Egea, Joaquim, Encinas, Mario
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2019
Pynciau:
Basic Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683709/
https://ncbi.nlm.nih.gov/pubmed/31300484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018111085
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg