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Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

BACKGROUND: Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects. Among the most potent inhibitors is the gene...

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Vydáno v:BMC Pharmacol Toxicol
Hlavní autoři: McGrath, Megan, Hofmann, Alissa, Raines, Douglas E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683373/
https://ncbi.nlm.nih.gov/pubmed/31383012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-019-0328-4
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