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Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

BACKGROUND: Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects. Among the most potent inhibitors is the gene...

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Pubblicato in:BMC Pharmacol Toxicol
Autori principali: McGrath, Megan, Hofmann, Alissa, Raines, Douglas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683373/
https://ncbi.nlm.nih.gov/pubmed/31383012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-019-0328-4
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