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Cigarette smoke activates the parthanatos pathway of cell death in human bronchial epithelial cells

Tobacco smoke negatively affects human bronchial epithelial (HBE) cells and is directly implicated in the etiology of smoking related respiratory diseases. Smoke exposure causes double-stranded DNA breaks and DNA damage activates PARP-1, the key mediator of the parthanatos pathway of cell death. We...

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Bibliografiske detaljer
Udgivet i:Cell Death Discov
Main Authors: Künzi, Lisa, Holt, Gregory E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683143/
https://ncbi.nlm.nih.gov/pubmed/31396404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0205-3
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