Cigarette smoke activates CFTR through ROS-stimulated cAMP signaling in human bronchial epithelial cells

Air pollution stimulates airway epithelial secretion through a cholinergic reflex that is unaffected in cystic fibrosis (CF), yet a strong correlation is observed between passive smoke exposure in the home and impaired lung function in CF children. Our aim was to study the effects of low smoke conce...

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Detalles Bibliográficos
Publicado en:Am J Physiol Cell Physiol
Main Authors: Wong, Francis H., AbuArish, Asmahan, Matthes, Elizabeth, Turner, Mark J., Greene, Lana E., Cloutier, Alexandre, Robert, Renaud, Thomas, David Y., Cosa, Gonzalo, Cantin, André M., Hanrahan, John W.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866379/
https://ncbi.nlm.nih.gov/pubmed/28978522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00099.2017
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