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Cigarette smoke alters primary human bronchial epithelial cell differentiation at the air-liquid interface

The differentiated human airway epithelium consists of different cell types forming a polarized and pseudostratified epithelium. This is dramatically altered in chronic obstructive pulmonary disease (COPD), characterized by basal and goblet cell hyperplasia, and squamous cell metaplasia. The effect...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Schamberger, Andrea C., Staab-Weijnitz, Claudia A., Mise-Racek, Nikica, Eickelberg, Oliver
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313097/
https://ncbi.nlm.nih.gov/pubmed/25641363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08163
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