Three-dimensional descriptors for aminergic GPCRs: dependence on docking conformation and crystal structure

ABSTRACT: Three-dimensional descriptors are often used to search for new biologically active compounds, in both ligand- and structure-based approaches, capturing the spatial orientation of molecules. They frequently constitute an input for machine learning-based predictions of compound activity or q...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Divers
Main Authors: Jastrzębski, Stanisław, Sieradzki, Igor, Leśniak, Damian, Tabor, Jacek, Bojarski, Andrzej J., Podlewska, Sabina
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682580/
https://ncbi.nlm.nih.gov/pubmed/30484023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11030-018-9894-4
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki