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Tools for Building, Analyzing and Evaluating HLA Haplotypes from Families
The highly polymorphic classical human leukocyte antigen (HLA) genes display strong linkage disequilibrium (LD) that results in conserved multi-locus haplotypes. For unrelated individuals in defined populations, HLA haplotype frequencies can be estimated using the expectation-maximization (EM) metho...
Shranjeno v:
| izdano v: | Hum Immunol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6682467/ https://ncbi.nlm.nih.gov/pubmed/30735756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2019.01.010 |
| Oznake: |
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