TEIPP peptides: exploration of unTAPped cancer antigens

The intracellular peptide pump TAP feeds antigenic peptides for loading onto HLA class I molecules, and its down-modulation is a frequent immune evasion mechanism in human cancers. Two recent papers describe which ‘hidden‘ antigens we might exploit to target these escaped cancer variants by CD8 T ce...

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Udgivet i:Oncoimmunology
Main Authors: Marijt, Koen A., Van Der Burg, Sjoerd H., van Hall, Thorbald
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682355/
https://ncbi.nlm.nih.gov/pubmed/31413908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1599639
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