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First Insight on Small Molecules as Cardiac Calsequestrin Stabilizers
[Image: see text] Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by mutations of cardiac calsequestrin (CASQ2) that impair its characteristic ability of Ca(2+)-induced polymerization–depolymerization. However, stabilizing the CASQ2 polymer by pharmacological agents to treat C...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6682146/ https://ncbi.nlm.nih.gov/pubmed/31460256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01113 |
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