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Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts.

Efficient delivery of therapeutic nanoparticles (TNPs) to tumors is critical in improving efficacy, yet strategies that universally maximize tumoral targeting by TNP modification have been difficult to achieve in the clinic. Instead of focusing on TNP optimization, here we show that the tumor microe...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Miller, Miles A., Chandra, Ravi, Cuccarese, Michael F., Pfirschke, Christina, Engblom, Camilla, Stapleton, Shawn, Adhikary, Utsarga, Kohler, Rainer H., Pittet, Mikael J., Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681815/
https://ncbi.nlm.nih.gov/pubmed/28566423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal0225
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