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Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts.

Efficient delivery of therapeutic nanoparticles (TNPs) to tumors is critical in improving efficacy, yet strategies that universally maximize tumoral targeting by TNP modification have been difficult to achieve in the clinic. Instead of focusing on TNP optimization, here we show that the tumor microe...

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Bibliografski detalji
Izdano u:Sci Transl Med
Glavni autori: Miller, Miles A., Chandra, Ravi, Cuccarese, Michael F., Pfirschke, Christina, Engblom, Camilla, Stapleton, Shawn, Adhikary, Utsarga, Kohler, Rainer H., Pittet, Mikael J., Weissleder, Ralph
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681815/
https://ncbi.nlm.nih.gov/pubmed/28566423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal0225
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