Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity

Chronic exposure to pesticides is implicated in the etiopathogenesis of Parkinson’s disease (PD). Previously, we showed that dieldrin induces dopaminergic neurotoxicity by activating a cascade of apoptotic signaling pathways in experimental models of PD. Here, we systematically investigated endosulf...

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Bibliographic Details
Published in:Toxicol Sci
Main Authors: Song, Chunjuan, Charli, Adhithiya, Luo, Jie, Riaz, Zainab, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
ENDOSULFAN NEUROTOXICITY AND PESTICIDE AOPs
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681683/
https://ncbi.nlm.nih.gov/pubmed/30796443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz049
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