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DNA barcoding a complete matrix of stereoisomeric small molecules

It is challenging to incorporate stereochemical diversity and topographic complexity into DNA-encoded libraries (DELs) because DEL syntheses cannot fully exploit the capabilities of modern synthetic organic chemistry. Here, we describe the design, construction, and validation of DOS-DEL-1, a library...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Gerry, Christopher J., Wawer, Mathias J., Clemons, Paul A., Schreiber, Stuart L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681660/
https://ncbi.nlm.nih.gov/pubmed/31184885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01203
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