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Unifying principles of bifunctional, proximity-inducing small molecules
Nature uses a variety of tools to mediate the flow of information in cells, many of which control distances between key biomacromolecules. Researchers have thus generated compounds whose activities stem from interactions with two (or more) proteins simultaneously. In this Perspective, we describe ho...
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| 發表在: | Nat Chem Biol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7312755/ https://ncbi.nlm.nih.gov/pubmed/32198490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0469-1 |
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