20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

20-HETE, an arachidonic acid metabolite synthesized by cytochrome P450 4A, plays an important role in acute brain damage from ischemic stroke or subarachnoid hemorrhage. We tested the hypothesis that 20-HETE inhibition has a protective effect after intracerebral hemorrhage (ICH) and then investigate...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: Han, Xiaoning, Zhao, Xiaochun, Lan, Xi, Li, Qian, Gao, Yufeng, Liu, Xi, Wan, Jieru, Yang, Zengjin, Chen, Xuemei, Zang, Weidong, Guo, Austin M, Falck, John R, Koehler, Raymond C, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2018
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681539/
https://ncbi.nlm.nih.gov/pubmed/29485354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18762645
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