20-HETE Regulates the Angiogenic Functions of Human Endothelial Progenitor Cells and Contributes to Angiogenesis In Vivo

Circulating endothelial progenitor cells (EPC) contribute to postnatal neovascularization. We identified the cytochrome P450 4A/F–20-hydroxyeicosatetraenoic acid (CYP4A/F–20-HETE) system as a novel regulator of EPC functions associated with angiogenesis in vitro. Here, we explored cellular mechanism...

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Detalhes bibliográficos
Main Authors: Chen, Li, Ackerman, Rachel, Saleh, Mohamed, Gotlinger, Katherine H., Kessler, Michael, Mendelowitz, Lawrence G., Falck, John R., Arbab, Ali S., Scicli, A. Guillermo, Schwartzman, Michal L., Yang, Jing, Guo, Austin M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935142/
https://ncbi.nlm.nih.gov/pubmed/24403517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.210120
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