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Migration promotes mutator alleles in subdivided populations

Mutator alleles that elevate the genomic mutation rate may invade nonrecombining populations by hitchhiking with beneficial mutations. Mutators have been repeatedly observed to take over adapting laboratory populations and have been found at high frequencies in both microbial pathogen and cancer pop...

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Bibliografske podrobnosti
izdano v:Evolution
Main Authors: Raynes, Yevgeniy, Sniegowski, Paul D., Weinreich, Daniel M.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680344/
https://ncbi.nlm.nih.gov/pubmed/30632605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/evo.13681
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